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b catenin inhibitor Patients with both primary gaze consecut
2019-06-10
Patients with both primary gaze consecutive esotropia (Fig. 1) and consecutive exotropia (Fig. 2) showed significantly less vertical deviation postoperatively compared with preoperative measurements (p Discussion The treatment of constant vertical tropia associated with consecutive horizontal dev
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Hydrogen peroxide H O is shown to readily promote
2019-06-10
Hydrogen peroxide (H2O2) is shown to readily promote EADs and triggered activity in isolated rat and rabbit ventricular myocytes by increasing both the L-type Ca channel (ICa-L) and late sodium currents (INa-L) [31–35]. However, this same stress fails to cause EADs in normal non-fibrotic cardiac tis
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br miRs and deregulation of bone
2019-06-10
miRs and deregulation of bone remodeling Bone remodeling can be affected by osteotropic cancers at a distance (e.g. pre-metastatic niches) or in close proximity. It has been hypothesized that osteolytic cancer Exendin-3 (9-39) amide produce various osteolytic factors (e.g. PTHrP) that stimulate o
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Economic sanctions have exacerbated the brutality
2019-06-10
Economic sanctions have exacerbated the brutality of this conflict many-fold, removing any prospects for peace and reconciliation. We need some reality to gauge their manifold effects before Syria descends into another Iraq, the devastating health consequences of which were well documented. Syria u
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Esto es visible no s lo
2019-06-10
Esto es visible no sólo en las notas necrológicas, sino también en los discursos que homenajean purchase KY02111 alguien en ocasión de su retiro o jubilación. En ellos encontramos rasgos comunes con las notas necrológicas, sobre todo en la idea de una herencia que deja el que se va, y que consiste e
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br Other drugs Overdose of diphenhydramine
2019-06-10
Other drugs Overdose of diphenhydramine (an H1 histamine receptor antagonist) is reported to induce a BrS phenotype [58,59]. Antihistamines are known to cause QT prolongation secondary to IKr inhibition. Cocaine is known to block the sodium rho kinase inhibitor and thus to unmask a BrS phenotype
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integrin inhibitors br Introduction Patients with advanced b
2019-06-10
Introduction Patients with advanced breast, prostate, lung and colo-rectal cancer frequently develop bone metastases (BMs). These lesions may be asymptomatic or may cause pain, pathologic fractures, malignant hypercalcemia, epidural spinal cord compression and/or shorten survival [1]. The underly
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The ability of tumors to progress to more malignant phenotyp
2019-06-10
The ability of tumors to progress to more malignant phenotypes depends on tumor microenvironment. Blood capillaries, made up of endothelial cells, are usually static under physiological conditions but are induced to proliferate by direct exposure to angiogenic factors, for instance, vascular endothe
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In several Western reports from
2019-06-06
In several Western reports from large-scale comparative studies and epidemiological surveys, there was no significant difference in the incidence of thromboembolism between paroxysmal and persistent AF patients [46,47]. Data from our institution suggested that the incidence of cardiogenic thromboemb
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br Catheter ablation A reentry circuit is supported by
2019-06-06
Catheter ablation A reentry circuit is supported by complex anatomy and a thick and/or damaged myocardium; thus, high-energy RF application is usually required to create the conduction block line through the critical isthmus of the reentry circuit in patients after ToF repair. A large-tip (8mm) a
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In focal coronary spastic angina intravascular ultrasound wa
2019-06-06
In focal coronary spastic angina, intravascular ultrasound was reported to detect intima–media complex thickening and an increased sonolucent zone [16,17], and OCT can detect intimal thickening with low lipid and calcium deposits [18], which are believed to reflect neointimal hyperplasia subsequent
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A year old man was hospitalized following
2019-06-06
A 36-year-old man was hospitalized following a first syncope attack while awake at night. No history of sudden death was reported in his family. On arrival, his consciousness was clear and his vital signs were stable. An electrocardiogram (ECG) showed sinus rhythm with ST-segment elevations and J wa
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Hereditary syndromes with increased risk for
2019-06-06
Hereditary syndromes with increased risk for gastric cancer include: 1) hereditary diffuse gastric cancer, 2) Lynch syndrome/hereditary non-polyposis colorectal cancer, 3) juvenile polyposis syndrome, 4) Peutz-Jeghers syndrome and 5) familial adenomatous polyposis. Hereditary diffuse gastric cancer
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Most women were found to be
2019-06-06
Most women were found to be unaware of possible prevention of the disease, including screening services for early detection and treatment of precancerous lesions. Some women affected by CC tend to initially seek treatment from traditional healers and use holy water. Beliefs concerning the cause of t
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Recently emerging data suggest that lower frequency of IV
2019-06-06
Recently emerging data suggest that lower frequency of IV bisphosphonates in metastatic breast cancer has the same efficacy as monthly regimen [48]. ONJ on the other hand can be extremely symptomatic with a severely detrimental effect on quality of life. A case-control study based on risk factors f
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