• This article is presented in six sections In

  2018-10-23

  

  This article is presented in six sections. In the following section, we provide some background on currency internationalization and the discussions on the use of vehicle currencies. Then, in Section 3, we describe our database and the methodology. Section 4 describes in which currencies the Brazili

• In this paper we assess the extent to which the

  2018-10-23

  

  In this paper we assess the extent to which the imposition of a no-arbitrage restriction on the DNS setting brings additional forecasting gains by providing an empirical evidence based on a large data set of constant-maturity future contracts of the Brazilian Inter Bank Deposit Contract (DI1) which

• Conflict of Interest br Extreme genetic variability

  2018-10-23

  

  Conflict of Interest Extreme genetic variability is the hallmark of HIV‐1 infection and it represents a major challenge for antiviral treatment and vaccine development. HIV‐1 group M dominates the global pandemic. Nine subtypes, 68 circulating recombinant forms (CRF) and countless unique recombin

• March marked Multiple Sclerosis MS

  2018-10-23

  

  March 2–8 marked Multiple Sclerosis (MS) Awareness Week in the United States MS is a chronic, often debilitating disease of the central caged compounds (CNS), affecting more than 2 million people worldwide. As recently as 25years ago, a diagnosis of MS came with no hope for course-altering treatmen

• Compared with previous studies the most interesting factor o

  2018-10-23

  

  Compared with previous studies, the most interesting factor of our study is its evaluation of telomere G-tail length. Associations between telomere G-tail length and total telomere length have been studied in human endothelial fiin from umbilical cord veins (HUVEC) (Anno et al., 2007). Here, we fou

• Following a thorough quality appraisal results

  2018-10-23

  

  Following a thorough quality appraisal, results from three studies were judged to be insufficiently credible for meta-analysis due to a lack of information presented about key components of their protocols (Bell and Orjasaeter, 1983; Fitzgerald et al., 1971; Kessel and Grossman, 1961). The quality o

• The current study was conducted primarily with the

  2018-10-23

  

  The current study was conducted primarily with the A32 antibody, together with a small number of sera from HIV-infected individuals. ADCC nicotinic acetylcholine receptor are among the first elicited following infection, as the gp120–CD4 interaction leads to exposure of cluster A epitopes. Not all s

• Cross talk between the various systems is

  2018-10-23

  

  Cross talk between the various systems is apparent with several well-described interactions such as that between C4-binding protein (C4BP) that regulates complement by inhibiting the classical initiation pathway and protein S, the latter being a cofactor for activated protein C, a regulator of coagu

• br The Role of Glucose Metabolism in HIV Pathogenesis br

  2018-10-23

  

  The Role of Glucose Metabolism in HIV Pathogenesis Metabolic Regulation of Monocytes Monocytes dramatically change their metabolic phenotype from oxidative to glycolytic metabolism when activated in humans (Dietl et al., 2010; Cramer et al., 2003), similar to what is observed in T cells. In a

• Treatment of recipients with the pro inflammatory

  2018-10-23

  

  Treatment of recipients with the pro-inflammatory PAMP, poly(I:C), prior to fresh HOD RBC transfusion resulted in alloantibody production comparable to the response to stored RBCs (Fig. 1e). It should be noted that this study did not directly address whether the demonstrated pro-inflammatory cytokin

• br CRISPR Cas Tips and Tricks

  2018-10-23

  

  CRISPR Cas9 Tips and Tricks Dario Lupianez and Malte Spielmann (Berlin, Germany) held an engaging workshop titled CRISPR Cas9 tips and tricks. The aim was to demonstrate how this genome editing technology can be utilized in embryonic stem flt3 (ESCs) to produce genomic structural variations (SVs

• Additionally we believe it would have

  2018-10-23

  

  Additionally, we believe it would have been valuable to investigate the presence of disturbed conditioned pain modulation (CPM) or inefficient descending pain inhibition in the chronic WAD group compared to controls. Subsequently, the efficacy of CPM could have been correlated with the rCBF of regio

• Although it can be hypothesized that brain alterations also

  2018-10-23

  

  Although it can be hypothesized that bace inhibitor alterations also play a role in the complex persistent complaints of patients with chronic whiplash-associated disorders (WAD), these changes remain poorly investigated. Therefore, the , recently published in , is of great scientific and clinical

• A surprising finding in the RV immune

  2018-10-23

  

  A surprising finding in the RV144 immune correlates analysis was that monomeric anti-Env IgA in plasma may mitigate otherwise protective IgG responses (Haynes et al., 2012, Tomaras et al., 2013). Both IgA and IgG antibody isotypes are key mediators of defense against pathogen invasion. Although IgG

• We identified two critical events that might be associated w

  2018-10-23

  

  We identified two critical events that might be associated with pathomechanism collagen VI deficiency in our mice. The first event is a non-cell-autonomous effect from the collagen VI deficiency, causing the dysregulation in the number of myofibers in a muscle. In normal control mice, myofibers incr

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