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A year old woman was referred to our medical center
2019-04-16
A 77-year-old woman was referred to our medical center for second opinion for refractory CMML-2. She had been incidentally found to have mild leukocytosis, anemia, and thrombocytosis on routine laboratory analysis. At diagnosis her white blood cell count (WBC) was 12×10/L, hemoglobin was 10.8g/dL, a
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Prior case reports have described hematological remission in
2019-04-16
Prior case reports have described hematological remission in patients with myelofibrosis during treatment with bisphosphonates, but a phase II study investigating the effects of zoledronic aa-dutp on patients with myelofibrosis showed responses in only 1 of 16 patients[13]. In conclusion, we report
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Despite our best efforts the
2019-04-16
Despite our best efforts, the cause of SCD in young individuals is sometimes not established; no cause is identified in up to 40% of cases. Importantly, whether a cause of death is established or not, the possibility of an underlying inherited cardiac disorder remains in many cases, including the po
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We modelled how the loss
2019-04-16
We modelled how the loss of health-care workers—defined here as doctors, nurses, and midwives—to Ebola might affect maternal, infant, and under-5 mortality in Guinea, Liberia, and Sierra Leone, with the aim of characterising the order of magnitude of likely effects, not providing specific prediction
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El libro de William Crawford publicado en traducido en
2019-04-16
El libro de William Crawford publicado en 1944, traducido en 1966, y las obras de Leopoldo Zea de 1949 y de 1965, aunque de muy distinto carácter y alcance, suscitaron primero un artículo de Oscar Kubitz en 1960, después un ensayo de Salomon Lipp en 1975, y, finalmente, otro artículo de frank Spindl
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La pol tica institucionalizada se convirti y
2019-04-16
La política institucionalizada se convirtió y se aceptó, por parte de los actores relevantes del sistema (neo-oligarquías e instituciones), y en gran medida por lo benevolente y bondadosa que sería para los intereses del gran capital, como el vehículo hacia el futuro del Estado. Se decretó que la cr
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AZD6244 Desde mediados de la d cada de los sesenta la
2019-04-16
Desde mediados de la década de los sesenta, la embajada argentina pedía informes sobre las actividades políticas en general y sobre las consideradas subversivas en Guatemala. A juicio de la embajada, en 1978 no se podía analizar la “ola de violencia” en Guatemala sin incluirla en el contexto de lo q
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Una vez que simplifican la problem tica latinoamericana
2019-04-15
Una vez que simplifican la problemática latinoamericana al ámbito de la violencia, dice el autor español, “lo único que parece interesar order TAPI-1 los de fuera es si el uso de la violencia está justificado o no”, y la respectiva petición de clarificación a los teólogos de la liberación funge como
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br Conclusion br Conflict of interest
2019-04-15
Conclusion Conflict of interest Introduction Classically, cancer has been described as a disease involving uncontrolled cell growth. Now, however, it is apparent that cancer growth and metastasis are not solely dependent on the tumor rsv virus themselves, but involve pathologies in the sur
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Subsequently more detailed mapping was performed
2019-04-15
Subsequently, more detailed mapping was performed to identify the Purkinje potential preceding the QRS onset of the PVCs in their region of origin (Fig. 2B). Radiofrequency ablation was performed at the site of the earliest Purkinje potential preceding the local ventricular potential (Fig. 2C and D)
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In contrast to adults PBL
2019-04-15
In sphingosine 1-phosphate receptor modulator to adults, PBL in children is regarded as a clinical entity that is distinct from its adult counterpart. Like many other pediatric malignancies, PBL is considered a systemic disease in children. In small retrospective studies, PBL in children is charact
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LQT can have numerous clinical manifestations ranging from n
2019-04-15
LQT1 can have numerous clinical manifestations, ranging from no symptoms to sudden cardiac death, which reflects the heterogeneity in channel dysfunction. Mutation type, location, and even a patient׳s ethnic background, age, and gender are critical factors that affect the pathophysiology of the dise
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Historically the introduction of caesarean section surgery
2019-04-15
Historically, the introduction of caesarean section surgery was associated with an improvement in maternal and perinatal health outcomes. WHO has stated that no empirical evidence exists for an ideal caesarean rate, but “what matters most is that all women who need caesarean sections actually receiv
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Introduction Atrial fibrillation AF is the most common cardi
2019-04-15
Introduction Atrial fibrillation (AF) is the most common cardiac arrhythmia encountered in clinical practice. The number of people with AF in the United States is currently estimated at 2.4 million, and the projected number with AF may exceed 10 million by 2050 [1,2]. Treatment for AF is also an im
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Discussion Mantle cell lymphoma is a distinct type of
2019-04-15
Discussion Mantle cell lymphoma is a distinct type of mature B-cell neoplasm that accounts for approximately 3–10% of non-Hodgkin\'s lymphoma. It is referred to several aliases, such as lymphocytic lymphoma of intermediate differentiation, mantle zone lymphoma, centrocytic lymphoma. Diffusion of no
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