• Senexin B SDCs and GPCs have been reported

  2018-10-24

  

  SDCs and GPCs have been reported to regulate cell adhesion, migration and differentiation and demonstrate specific expression and localisation during CNS development (Choi et al., 2011, Ford-Perriss et al., 2003). The depletion of SDC1, GPC1 and GPC4 in vitro in mouse NSC or neural precursor cells a

• Alternatively and our data support this as

  2018-10-24

  

  Alternatively, and our data support this as the most likely explanation, eYFP+ cells may arise from nestin expression by extant mature neurons. Nestin is an intermediate-sized cytoskeletal protein that is important for cell remodeling, particularly in developing and regenerating tissues. In the rode

• br Results br Discussion Here we describe

  2018-10-24

  

  Results Discussion Here we describe the role for histone demethylases KDM4A and KDM4C in the epigenetic regulation of mESC differentiation to endothelial cells. We showed that KDM4A and KDM4C targeted the tri-methyl histone 3 lysine 9 (H3K9me3), a known repressive marker of gene regulation (Bl

• We and others have shown previously that the evolutionarily

  2018-10-24

  

  We and others have shown previously that the evolutionarily conserved Notch signaling pathway plays an important role in early embryonic pituitary development (Kita et al., 2007; Raetzman et al., 2004, 2007; Zhu et al., 2006). Delta/Notch signaling, mediated by the critical transcription factor RBP-

• EWS FLI a widely recognized

  2018-10-24

  

  EWS-FLI1, a widely recognized fusion oncogene for Ewing sarcomas, is generated by the chromosomal translocation of t(11;22) (q24;q12), which consists of the N-terminal transactivator domain of the EWS gene and the C-terminal ETS DNA binding domain of the FLI1 gene. The resulting EWS-FLI1 fusion prot

• br Results br Discussion In this study we

  2018-10-24

  

  Results Discussion In this study, we identified the existence of non-neuronal ACS in developing prostate epithelium. Activation of ACS promoted the proliferation of epithelial progenitor hif inhibitor and inhibited their differentiation to luminal cells. On the contrary, blockade of CHRM3 eff

• DENV as one of the most widespread vector borne viruses

  2018-10-24

  

  DENV, as one of the most widespread vector-borne viruses, infects millions of people each year worldwide. However, no clinically approved drugs are yet available against DENV. There is an urgent need to develop effective anti-DENV drugs for such treatment. In this study we tested IFN-α2a, chloroquin

• br Experimental Procedure br Author

  2018-10-24

  

  Experimental Procedure Author Contributions Introduction The human heart develops as the first functional organ in the embryo. In the lateral plate mesoderm (LPM) cardiac progenitor carnitine palmitoyltransferase are induced, which can subsequently differentiate into heart muscle cells (car

• IGF and PI K signaling in regenerating muscle was tightly

  2018-10-24

  

  IGF and PI3K signaling in regenerating muscle was tightly regulated across multiple levels and temporally, especially during the transition between myoblast proliferation and differentiation. In the early period, IGF1 was upregulated and quickly followed by increases in expression and chromatin remo

• Mixed populations of PSCs were also converted to naive

  2018-10-24

  

  Mixed populations of PSCs were also converted to naive PSCs in 2i + LIF medium without serum or to primed EpiLCs in bFGF + activin medium. EpiLCs induced from ESCs expressed only RFP, and the RFP+ EpiLCs were indistinguishable from EpiSCs in terms of morphology, gene expression patterns, epigenetic

• Hippocalcin HPCA is a high affinity calcium binding protein

  2018-10-24

  

  Hippocalcin (HPCA) is a high-affinity calcium-binding protein restricted to the CNS and is most abundant in pyramidal cells of the hippocampus CA1 region (Kobayashi et al., 2012). During brain development HPCA expression increases sharply, concurrent with synapse formation (Saitoh et al., 1994). HPC

• Human liver chimeric mice carrying human pHH can

  2018-10-24

  

  Human liver chimeric mice carrying human pHH can facilitate in vivo study of viral hepatitis infections (Bissig et al., 2010; Carpentier et al., 2014) and liver genetic diseases (Bissig-Choisat et al., 2015; Yusa et al., 2011), and the testing of small molecular drug candidates and biological compon

• br For an isolated particle n where n is

  2018-10-24

  

  For an isolated particle, 0 = 0 = n0, where n0 is the concentration of charged particles in unperturbed plasma; besides, the thickness r0 of the perturbed region for that particle is not known in advance. The charge (the potential) of the particle in the steady-state case is determined by the cha

• There are currently several known mechanisms for generating

  2018-10-24

  

  There are currently several known mechanisms for generating terahertz radiation, based on impurity-assisted transitions of charge carriers in semiconductors and semiconductor nanostructures. For example, terahertz apoptosis was observed during optical transitions of nonequilibrium charge carriers i

• Calculation scheme According to Buckingham s

  2018-10-24

  

  Calculation scheme. According to Buckingham\'s theory for a system of two polar components, the following relationships hold true: where ε is the dielectric permittivity; n is the refractive index; V is the molar volume, V= ( is the specific volume; М is the molecular weight); х is the molar fract

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