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Obtaining direct access to all
2018-11-12

Obtaining direct access to all three types of actual projects is difficult; therefore, we seek assistance from other researchers. Case 1 (Li, 2012) and 3 (Sun, 2006) have been analyzed in previous studies, and the details of energy data are sufficient for our analysis. For Case 2, we conducted field
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Under ROC curve analysis the cutoff value
2018-11-12

Under ROC curve analysis, the cutoff value in fascia defect width/abdominal circumference ratio was 13.99% with high sensitivity and specificity (100% and 100%, respectively). All cases with fascia defect width/abdominal circumference ratio larger than 13.99% showed complications of different extent
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br Materials and methods We revised
2018-11-12

Materials and methods We revised a set of criteria for TPA to include (1) Glasgow Coma Scale (GCS) score ≤13, (2) systolic blood pressure (BP) ≤90 mmHg, (3) fall of more than 6 m in height, and (4) head, neck, or torso gunshot wound (Table 1). When an injured patient meets the TPA criteria, the t
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guanylyl cyclase br Materials and methods br Results br Disc
2018-11-12

Materials and methods Results Discussion The main goal of current investigation was to study the role of oxygen in the maintenance of LESC phenotype under conditions of biochemically undefined and a serum-free highly defined growth environment. The oxygen concentrations used in the present
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Both CAR and DAF have been
2018-11-12

Both CAR and DAF have been implicated in CVB infection. Molecular events underlying CVB entry have been described for polarized (Coyne and Bergelson, 2006) and nonpolarized monensin cost (Patel et al., 2009). However, the exact mechanism involved in CVB infection of cardiomyocytes is unknown. Moreov
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The objective of this work
2018-11-12

The objective of this work was to investigate if a synergistic coculture system of MSCs with endothelial Tubastatin A Supplier could affect the number and state of differentiation of harvested MSCs. In contrast to other papers, in this cell-cell communication topic, the investigation was carried out
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The neuroprotective effect of hypoxic
2018-11-12

The neuroprotective effect of hypoxic preconditioning in the sphingosine kinase has been studied by several groups who found evidence for the involvement of HIF-1α and its downstream targets and/or Epo (He et al., 2008) (Liu et al., 2005; Theus et al., 2008) (Prass et al., 2003) (Bernaudin et al.,
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To address the question of whether these HLCs
2018-11-12

To address the question of whether these HLCs could serve in cellular therapies, a variety of markers of hepatocyte differentiation were considered. For example, production of albumin, a classic marker of hepatocyte differentiation, was observed in HLCs (Fig. 2). However, production of albumin has b
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An approach that has shown promise for answering these
2018-11-12

An approach that has shown promise for answering these types of questions in other stem cell systems, and is becoming increasingly feasible with advanced computing power and improved tracking algorithms, is long-term in vitro imaging of individual stem and progenitor cells (Schroeder, 2011). Long-te
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Since the first report of induced
2018-11-12

Since the first report of induced pluripotent stem (iPS) purchase CB-5083 generated by the expression of four transcription factors Oct4, Sox2, Klf4 and c-Myc (OSKM) in fibroblasts (Takahashi and Yamanaka, 2006), there has been a variety of technical improvements to generate iPS cells more efficien
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br Materials and methods br Acknowledgements We
2018-11-12

Materials and methods Acknowledgements We would like to thank Dr. Keisuke Okita and Prof. Shinya Yamanaka for providing the plasmids. Furthermore, we would like to thank Prof. Duncan R. Smith for proof reading the article. This work was supported by the Thailand Research Fund (MRG5980187), Nat
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Additionally it would be highly
2018-11-12

Additionally, it would be highly desirable to manipulate CSCs to improve their survival and direct them efficiently to the myocyte lineage. A recently developed technology to deliver mRNA in vivo shows promise. Modified RNA (modRNA) encoding human vascular endothelial growth factor-A (VEGF-A) improv
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br Materials and methods br Results br
2018-11-12

Materials and methods Results Discussion It is known that mutation types of SOD1 affect not only enzymatic activity and protein half-life of SOD1, but also age at onset and the survival time of SOD1-ALS patients (Hayward et al., 2002) (Borchelt et al., 1994) (Regal et al., 2006). However, t
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where a is a radius of the circular contact probe
2018-11-09

where a is a radius of the circular contact (probe); r is a distance from the center of the contact – probe place to the hemispherical contact; ρ is a resistivity of the area between the contacts. Spreading resistance R is well approximated for a homogeneous semi-infinite doped sample with resistan
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The C terminal sequence is crucial for maintaining the struc
2018-11-09

The C-terminal sequence 209–223 is crucial for maintaining the structure of the active site, with its deletions leading to loss of the ligand-binding properties [49]. The carboxyl terminus of the first transmembrane domain TM1 is also involved in the formation of the binding site through close inte
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