• The enzyme plays an important

  2024-05-22

  

  The enzyme plays an important role in the purine metabolism of this parasite. Like other parasitic protozoa, T. gondii is incapable of de novo purine biosynthesis and depends totally on preformed purines salvaged from the host BI-847325 for its purine requirements and survival (Perrotto et al., 197

• Although our data show that agrin accelerates the innervatio

  2024-05-22

  

  Although our data show that agrin accelerates the innervation of engineered muscle tissue following implantation, there are still several issues that need to be considered. First, the use of primary muscle stem or progenitor Bialaphos sodium salt (satellite cells) instead of an immortalized muscle

• Physiological total plasma LPA levels are normally

  2024-05-21

  

  Physiological total plasma LPA levels are normally less than 1μM in healthy subjects. LPA levels have been reported to be increased in malignant effusions or plasma in cancer patients [20]. In addition, increasing ATX activity detected in healthy pregnant women in the third trimester of pregnancy ex

• If the lack of specificity and the high pleiotropy

  2024-05-21

  

  If the lack of specificity and the high pleiotropy may represent a problem in view of the potential chemotherapeutic features of autophagy-inducing agents, it zilpaterol may switch into an advantage in the case of chemopreventive strategies. In fact, as non-pharmacologic interventions such as limite

• br Structure of V ATPase V ATPase is

  2024-05-21

  

  Structure of V-ATPase V-ATPase is a highly conserved multi-subunit enzyme that uses energy from ATP hydrolysis to transport protons across membranes [2], [3], [4]. It consists of two major functional domains, V1 and V0 (Fig. 1). The former has eight different subunits (A, B, C, D, E, F, G, and H)

• The tumor suppressor function of LOX

  2024-05-21

  

  The tumor-suppressor function of 15-LOX-2 in normal prostate epithelial cells may be explained by the induction of replicative senescence [14,15]. Thus, 15-LOX-2 is overexpressed in age-dependent prostatic hyperplasia, but cell senescence may hinder progression to malignant transformation. Notwithst

• Introduction Initially postulated to represent the main sour

  2024-05-21

  

  Introduction Initially postulated to represent the main source of ATP production in eukaryotic cells, mitochondria are recently recognized to perform manifold essential functions beyond energy production, impacting most areas of cell biology and medicine [1]. Mitochondrial metabolism is both the ba

• Once apoptosis has been initiated the HMGA proteins

  2024-05-21

  

  Once apoptosis has been initiated the HMGA proteins themselves undergo marked changes in both the types and extent of their post-translational modifications (PTMs; review in [149,175]), some of which are likely correlated with alterations in chromatin structure. For example, the early stages of apop

• The basis for the protonation

  2024-05-21

  

  The basis for the protonation of chitosan is the alkaline primary amino group, which is also the reason for the special properties of chitosan (Guibal, Van Vooren, Dempsey, & Roussy, 2006; Tamer et al., 2017; Yang et al., 2014). Our previous work (Meng et al., 2012) and several other reports (Yan et

• PGC mediated mitochondrial biogenesis in brown fat

  2024-05-21

  

  PGC-1α-mediated mitochondrial biogenesis in brown fat and endothelial Sunitinib Malate synthesis is in part regulated by eNOS and NO [28], [29]. Recent studies indicate that H2S not only augments NO bioavailability and signaling [11], [17], but provides protection against cardiac injury in an eNOS-

• BINA The RE compartment has been shown to be

  2024-05-21

  

  The RE compartment has been shown to be critical for supplying AMPAR during LTP (Hanley, 2010; Park et al., 2004), but whether they also supply AMPAR for synaptic scaling has been less clear (Gainey et al., 2015; Tan et al., 2015). Interestingly, although an increase in μ3A is necessary for scaling,

• br Materials and methods br Results

  2024-05-21

  

  Materials and methods Results and discussion First, we examined whether hypothalamic Akt-mediated signaling pathways are regulated postprandially in chickens. Refeeding significantly (P imidazole receptor concentrations significantly increased in chicks after 1 h of refeeding (958 ± 245% of 2

• br Materials and methods br Results

  2024-05-20

  

  Materials and methods Results Discussion In this study, we have demonstrated that the adiponectin system (genes and proteins) is present in the porcine endometrium (epithelial glandular cells, luminal epithelial L-Cysteinesulfinic acid sale and stromal cells) and myometrium (longitudinal a

• The ARHL locus ahl that contributes to the hearing

  2024-05-20

  

  The ARHL locus (ahl) that contributes to the hearing loss in the C57BL/6J mouse has been mapped to chromosome 10 (Erway et al., 1993, Johnson et al., 1997). It has been shown that strains susceptible to early onset ARHL carry a specific mutation in the cadherin 23 gene (Cdh23), which encodes a compo

• ACh induced changes in respiratory

  2024-05-20

  

  ACh-induced changes in respiratory frequency could be of interest. They may reveal an important mechanism of respiratory modulation at the caudal NTS level. ACh-induced increases in respiratory frequency within this region have been also reported by Furuya et al. (2014). Changes in respiratory timin

16325 records 147/1089 page Previous Next First page 上5页 146147148149150 下5页 Last page