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In addition to the potential for adverse effects of
2019-04-25
In addition to the potential for adverse effects of poor growth on brain outcomes in this cohort, the prevalence of iron deficiency was also alarmingly high. All the hospitals recommended iron supplements at discharge and throughout the intervention period, but levels of compliance could not be dete
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Adenosine is an important factor to participate
2019-04-25
Adenosine is an important factor to participate the generation of ATP. What’s more, adenosine has significant endogenous protective effect such as suppressing the release of excitatory amino acid, reducing the permeability of cell membrane to calcium ion, expanding blood vessel of brain, preventing
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In this study SPR AIRS was
2019-04-25
In this study, SPR-AIRS was applied to screen p38 ligands from herbal extracts. p38 is an important drug target, which plays a key role in cell proliferation, apoptosis and tumorigenesis [22]. Firstly, recombinant p38 protein was immobilized on SPR chip, the activity and feasibility of the chip was
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br Mega cohort studies Remote monitoring collects a wealth o
2019-04-25
Mega-cohort studies Remote monitoring collects a wealth of data from large numbers of patients which are not subject to saturation or overwritten memory counters within any implantable device. These databases provide an opportunity to better understand system function, patient condition, and dise
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The standard therapy for chordoma is
2019-04-25
The standard therapy for chordoma is excision. Local recurrence, but not metastasis, is a major determinant of prognosis. Because local recurrence is related to initial surgical margin and intra-operative tumor cell contamination, achieving a safe margin is very important. Boriani [6] reported 153 c
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A type saddle back type or type ST
2019-04-25
A type 2 (“saddle-back type”) or type 3 ST-segment elevation cannot substitute for a type 1, unless converted to type 1 with fever or sodium drug challenge. A drug challenge–induced type 1 can be used to diagnose BrS only if accompanied by 1 of the criteria specified above. Type 2 is characterized b
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LQT can have numerous clinical manifestations ranging from n
2019-04-25
LQT1 can have numerous clinical manifestations, ranging from no symptoms to sudden cardiac death, which reflects the heterogeneity in channel dysfunction. Mutation type, location, and even a patient׳s ethnic background, age, and gender are critical factors that affect the pathophysiology of the dise
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membrane transport Polymorphic VT VF storms can occur in pat
2019-04-24
Polymorphic VT/VF storms can occur in patients with severe membrane transport failure, independent of their underlying causes. Recent experimental studies using a pacing-induced heart failure model showed that heart failure facilitates acute shortening of the APD immediately after VF termination [7
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br Conclusions br Study limitations
2019-04-24
Conclusions Study limitations Conflict of interest Introduction Dabigatran etexilate, an orally administered pro-drug, is rapidly converted by a serum esterase to dabigatran, a potent, direct, and competitive inhibitor of thrombin. It has an absolute bioavailability of 6.5% and a serum b
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Residing in West Germany also
2019-04-24
Residing in West Germany also decreased BIS persistence. In 2015, Jacob et al. demonstrated in 4,915 BC women that the treatment discontinuation rate is higher in West Germany than in East Germany [1]. Finally, our study returned one outcome that requires careful discussion: we found that private he
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Our two groups of patients were similar in all but
2019-04-24
Our two groups of patients were similar in all, but two, parameters: the non-inducible group had a significantly higher prevalence of atrial fibrillation (Table 1) and a significantly lower use of β-blockers at the time of enrollment into the study (discharge time after PES only or ICD implantation)
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Tentativas de encontros frequentes os debates e
2019-04-24
Tentativas de encontros frequentes, os debates e as polêmicas contribuem para Cyanine5.5 alkyne consolidação efetiva de um projeto coletivo em torno dos objetivos editoriais e políticos de uma revista. No caso de Araucaria de Chile, no que concerne às representações sobre as revoluções cubana e sand
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br Discussion Valproic acid is a
2019-04-24
Discussion Valproic order NHS-SS-Biotin is a potent inhibitor of histone deacetylases (HDAC). It can modify the structure of chromatin allowing recruitment of transcription factors to restore epigenetically suppressed genes. Valproic acid has been shown to possess antiproliferative activity and
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Methods We used data from
2019-04-23
Methods We used data from meta-analyses from the fields of climate change, agriculture, economics, nutrition, and neurology referenced in the UN Intergovernmental Panel on Climate Change fifth Assessment Report and obtained via a Web of Science search in January, 2015. We constructed a model of thes
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br We recently reported associations between
2019-04-23
We recently reported associations between maternal age at childbirth and outcomes in the offspring, using data from five birth cohorts (COHORTS collaboration) in low-income and middle-income countries (LMICs), in . Young maternal age ( Antimicrobial resistance is recognised as a serious global he
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